1)   SayPad 1.0
SayPad, the freeware talking text editor can read you a good book or help you write one, using SAPI 5.1 Text To Speech (included). It can convert Text to MP3 for a whole book in one run, splitting off chapters into well named MP3 files.

 2)   4BlindMice 1.4
Real Time Screen Reading talking mouse works with existing reader to provide GUI. Run your hands over the screen and get the big picture. Drive your mouse full speed across the screen, knowing in real time where you are and what you're flying over.

 3)   Metris 1.0
Metris is an accessible Musical Tetris game. Beating this game you are able to quickly recognize scales, modes and chords. No jargo, just music. Anyone can do it... but how well? Do you have what it takes to become a Metris Master?